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Project Investigator Biography

Phillip Koeffler, M.D. Phillip Koeffler, M.D.

University of California, Los Angeles
Department of Medicine/Hematology-Oncology
10833 Le Conte Avenue, 11-937 CHS,
Los Angeles, CA 90095-1678
phone: (310) 423-4609
fax: (310) 423-0443

Dr. Koeffler is Professor of Medicine at UCLA and the Chief of the Division of Hematology-Oncology at Cedars Sinai Medical Center in Los Angeles. Since 2005, he has been the Principle Investigator from UCLA in the PACHE partnership with King Drew University in Los Angeles involved in Center to Reduce Cancer Health Disparities.

In collaboration with Dr. Vadgama, co-PI on the UCLA-Drew University PACHE partnership, he has been studying a series of secreted proteins in breast cancer known as CCN proteins. Breast cancer produces high levels of these proteins which can then in an autocrine fashion stimulate growth of the breast cancers. This study of breast cancer in African Americans is particularly important because of the aggressive nature of this disease. In addition, to these studies, he has an outstanding record in cancer research, with over 640 publications and over 100 book chapters. Most of his manuscripts are in peer-reviewed journals and most that have an impact factor over 6.5. At any one time for the last 15 years, Dr. Koeffler has had 15 – 20 post-docs working in his laboratory with about 1/3 being Ph.D.s; 1/3 M.Ds, and 1/3 having M.D.s and PhDs. Students are also in the lab including those who are taking a year off between undergraduate and either medical or pharmacy school or graduate school, as well as, those who are university undergraduates. During the summer, the lab has one or several high school students.

Dr. Koeffler has had the same RO1 for 30 year. He is an investigator on a NIH Sponsored Program Project grant for over 12 years. Dr. Koeffler was the PI on a Program Project grant from NIH for 10 years. He has had numerous additional RO1 grants, as well as smaller two to three year grants awarded through NIH or DOD. Furthermore, he has an endowed chair entitled, “Mark Goodson Endowed Chair for Cancer Research” that helps support his salary. Since 1978, Dr. Koeffler has trained over 110 post-docs, probably a similar number of university students and has had two M.D/Ph.D., candidates who received their Ph.D.s in his laboratory

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Other Project Investigator
Jaydutt Vadgama, M.D. PhD.
Updated: 05/22/13