Project Investigator Biography
Susan Naylor, Ph.D.
University of Texas Health Science Center – San Antonio
University of Texas Health Science Center, San Antonio,
Dept. of Cellular & Structural Biology,
7703 Floyd Curl Drive, MD 7762,
San Antonio, TX 78229
Susan Naylor, Ph.D. is a Professor of Cellular and Structural Biology at the University of Texas Health Science Center at San Antonio. Dr. Naylor is the Associate Director of Shared Resources and Education for the Cancer Center. Dr. Naylor became the PI of the PACHE partnership between the University of Texas Pan Am and the Health Science Center in 2008.
Dr. Naylor is the leader of the Cancer Biology Track of the Integrated Multidisciplinary Graduate Program and the Chair of the Committee on Graduate Studies (COGS) for the Department of Cellular & Structural Biology. Because of her active interest in education, Dr. Naylor is directing the summer program for the students from the University of Texas Pan Am in Edinburg, TX. Dr. Naylor is a cancer geneticist and she is well known for her role in the genome project sequencing human chromosome 3. She is recognized for her cancer research and is listed in ISIHighlyCited.com.
In early studies with chromosome 3, she found that the middle of the short arm of chromosome 3 is frequently deleted in many types of cancer including lung, ovarian, head and neck, and uterine cancer. Using a combination of analysis of tumor samples and a functional assay for tumor suppression, this region was limited to 80Kb of human DNA. Two related genes in this region: semaphorin 3F and semaphorin 3B not only suppress tumor growth in nude mice, but also alter in vitro tumorigenic properties of several tumor types. Dr. Naylor’s research is directed towards defining the role of these two genes in tumorigenesis. A translational project has spun off this research. Two common missense variants in the region as well as other SNPs (single nucleotide polymorphisms) are being examined for an association with prostate cancer in Hispanic males. Dr. Naylor and colleagues have found that many markers in this region are associated with increased cancer risk as well as a poorer prognosis. The goal of this project is to define genetic markers that predict increased risk or a poorer prognosis in the Hispanic population of South Texas.View Partnership Abstract Description
Other Project Investigator
Bimal Banik, Ph.D.