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Project Investigator Biography

W. Jack Pledger, Ph.D. W.Jack Pledger, Ph.D.

H. Lee Moffitt Cancer Center
12902 Magnolia Drive,
Tampa, FL 33612
phone: (813) 745-3887
fax: (813) 745-6700
email: jack.pledger@moffitt.org

Dr. Jack Pledger is Deputy Director and Executive Vice President/Associate Center Director Basic Science & NFGC Director. He has published in top peer-reviewed journals of his field and has been an associate editor for the Journal of Cellular Biochemistry, Critical Reviews in Eukaryotic Gene Expression and Cancer Research. He has served as a permanent member on NIH, ACS, and VA grant review panels and has served on numerous NIH and NCI ad hoc panels for review of Program Project Grants and Center Grants. In addition, he has served on the external advisory boards of Vanderbilt Ingram Cancer Center, Hollings Cancer Center, University of Oklahoma Cancer Center and the University of Tennessee Cancer Institute. In 2001, Dr. Pledger was the first recipient of Moffitt Cancer Center's Scientist of the Year Award. Dr. Pledger is a member of the Molecular Oncology Program and Professor in the Oncological Sciences Department and holder of the Cortner-Couch Chair for Cancer Research. He is also, the founding Director of the National Functional Genomics Center at Moffitt Cancer Center.

Dr. Pledger has provided leadership and direction for the development of Basic Research and has helped put together the research effort that supports the Moffitt Mission and our comprehensive designation. His primary goal is to establish research programs that will ultimately lead to the cure of cancer. His research interests focus on the mechanisms that regulate cellular proliferation, differentiation, apoptosis and tumor development.

Prior to joining the Moffitt Cancer Center, Dr. Pledger spent ten years as a Professor, in the Department of Cell Biology at Vanderbilt University School of Medicine in Nashville, Tennessee. He was previously on the faculty of the Lineberger Cancer Center at the University of North Carolina’s School of Medicine. Dr. Pledger received his Ph.D. degree from Purdue University, West Lafayette, Indiana. He did postdoctoral training at M.D. Anderson Hospital and Tumor Institute in Houston, TX and the Dana Farber Cancer Center at Harvard University School of Medicine in Boston, MA.

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Other Project Investigator
Manuel Torres-Ruiz, Ph.D.
Updated: 04/30/12